- Dance Companies, Depew
- Data Processing Services, Depew
- Defensive Driving Schools, Depew
- Delicatessen Restaurants, Depew
- Dental Bonding & Cosmetic Dentistry, Depew - Cosmetic Dentist & Tooth Bonding
- Dentists, Depew
- Deodorant, Disinfectants & Germicides, Depew
- Department Stores, Depew
- Developmental Children Services, Depew
- Developmental Disabilities, Depew
- Developmentally Disabled Information & Services, Depew
- Diner Restaurants, Depew
- Direct Mail Advertising, Depew
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- Direct Mail Advertising Services, Depew
- Disc Jockeys, Depew
- Discount Stores, Depew - Clothing, Grocery, Furniture, Etc
- Disease, Handicap & Disability Services, Organizations & Groups, Depew
- Diving Equipment & Supplies, Depew - Scuba & Snorkel Gear & Masks Shops
- Divorce & Family Law Attorneys & Lawyers, Depew
- Doctors, Physicians & Surgeons, Depew
- Donuts, Depew
- Drinking Establishments, Depew
- Drug Screening Services, Depew
- Dry Cleaning & Laundry, Depew - Dry Cleaners
- Durable & Non Durable Goods & Products, Depew
- Durable Goods & Products, Depew
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