- Safety & Security Systems & Consultants, Islip
- Salvage Yards, Junk Yards & Wrecker Service, Islip
- Sandwich Shop Restaurants, Islip
- Satellite Descrambling & Programming Service, Islip
- Satellite Dish Antennas & Equipment Dealers, Islip
- Satellite TV Service, Islip
- Scaffolding & Aerial Lifts, Islip
- Scottish & Irish Goods & Products Stores, Islip
- Secondary Schools, Islip
- Secretarial & Court Reporting Services, Islip
- Security & Surveillance System & Equipment, Islip
- Security Alarm Systems - Home & Business, Islip
- Security Control Systems & Monitoring, Islip - Polygraph, Lie Detector, CCTV, Fire Sensor Equipment, Etc
- Security Management Consultants, Islip
- Security Services, Islip
- Service & Gas Station Equipment & Services, Islip
- Shoe Shining, Islip
- Shopping & Shopping Services, Islip
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- Siding Contractors, Islip - Vinyl Siding, Wood, Metal & Aluminum Siding Contractors - Installation & Repair
- Skin Care & Cosmetology Salons, Islip
- Skin Care Products & Treatments, Islip
- Small Appliances, Islip
- Snacks & Desserts, Islip
- Social Services & Welfare, Islip
- Societies & Foundation Associations, Islip
- Special Events & Party Supply Rental, Islip
- Special Interest Schools Or Instruction, Islip
- Specialty Animal Services, Islip
- Specialty Stores, Islip
- Speech & Hearing Specialists, Islip
- Sporting Goods Stores, Islip
- State Government, Islip
- Stationery & Office Supplies, Islip
- Steak House Restaurants, Islip
- Surveyor Services, Islip - Surveying Service
- Swimming Pools Repair, Service, Supplies, Sale & Installation, Islip
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