- Safety & Security Contractors, Margaretville
- Sand Gravel & Aggregate, Margaretville
- Seafood Restaurants, Margaretville
- Secondary Schools, Margaretville
- Security & Surveillance System & Equipment, Margaretville
- Security Services, Margaretville
- Septic Tank Installation & Repair, Margaretville - Septic Systems
- Septic Tank Pumping & Cleaning, Margaretville - Septic Systems
- Septic Tanks & Septic Systems Contractors, Margaretville - Installation, Repair, Service, Cleaning & Pumping Septic Tanks
- Sewing & Yarn Stores & Supplies, Margaretville
- Shoe Stores, Margaretville - Mens, Womens & Kids Shoes
- Shopping & Shopping Services, Margaretville
- Signs, Margaretville
- Snacks & Desserts, Margaretville
- Snow Removal Services, Margaretville - Snow Plow Service
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- Social Services & Welfare, Margaretville
- Social Workers & Services, Margaretville
- Societies & Foundation Associations, Margaretville
- Specialty Animal Services, Margaretville
- Specialty Stores, Margaretville
- Sporting & Recreational Camps, Margaretville
- Sporting Goods Equipment Rental, Margaretville
- Sports & Recreational Services, Margaretville
- State Government, Margaretville
- Steak House Restaurants, Margaretville
- Storage Containers, Margaretville
- Stucco Siding Contractors, Margaretville - Stucco Repair & Installation
- Stucco Siding, Granite & Grouting Contractors, Margaretville
- Surveyor Services, Margaretville - Surveying Service
- Swimming Pools Supplies, Equipment & Accessories, Margaretville
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