- Sales & Marketing Consultant, Port Jefferson Station
- Sandwich Shop Restaurants, Port Jefferson Station
- Savings Banks, Port Jefferson Station
- Scrapbooks & Scrapbook Supplies, Port Jefferson Station
- Screen Printing, Port Jefferson Station
- Seafood Restaurants, Port Jefferson Station
- Security & Surveillance System & Equipment, Port Jefferson Station
- Security Alarm Systems - Home & Business, Port Jefferson Station
- Security Brokers & Dealers, Port Jefferson Station
- Security Control Systems & Monitoring, Port Jefferson Station - Polygraph, Lie Detector, CCTV, Fire Sensor Equipment, Etc
- Security Investigative Services, Port Jefferson Station
- Security Services, Port Jefferson Station
- Self Defense Programs, Port Jefferson Station
- Service Establishment Supplies & Equipment, Port Jefferson Station
- Sewer & Drain Cleaning & Repair, Port Jefferson Station - Drain Cleaner & Installation Services
- Sheet Metal Contractors, Port Jefferson Station - Sheet Metal Fabrication
- Sheet Metal Fabricators & Ductwork Contractors, Port Jefferson Station
- Shirts & T-Shirts, Port Jefferson Station
- Shoe Dyers, Port Jefferson Station
- Shoe Repair Shops, Port Jefferson Station
- Shoe Stores, Port Jefferson Station - Mens, Womens & Kids Shoes
- Shopping & Shopping Services, Port Jefferson Station
- Siding Materials, Port Jefferson Station
- Signs, Port Jefferson Station
- Sleds, Snowboards & Snowshoes Shops, Port Jefferson Station - Snow Sleds, Toboggans, Helmets, Boots, Goggles, Clothing, Gear & More
- Smoothie Restaurants, Port Jefferson Station
- Snacks & Desserts, Port Jefferson Station
- Social Clubs & Organizations, Port Jefferson Station
- Social Services & Welfare, Port Jefferson Station
- Social Workers & Services, Port Jefferson Station
- Societies & Foundation Associations, Port Jefferson Station
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- Spare Rib Restaurants, Port Jefferson Station
- Special Events & Party Supply Rental, Port Jefferson Station
- Special Interest Schools Or Instruction, Port Jefferson Station
- Specialty Animal Services, Port Jefferson Station
- Specialty Stores, Port Jefferson Station
- Speech & Hearing Specialists, Port Jefferson Station
- Speech & Language Therapy, Port Jefferson Station
- Sporting Goods Equipment Rental, Port Jefferson Station
- Sporting Goods Stores, Port Jefferson Station
- Sports Clubs, Port Jefferson Station
- Sports Medicine, Port Jefferson Station - Doctors, Physicians & Surgeons
- Sprinkler Alarm Systems, Port Jefferson Station - Fire Sprinkler Systems
- Sprinkler System Contractors, Port Jefferson Station - Garden & Lawn Sprinkler System Installation & Repair
- Staffing & Support Services, Port Jefferson Station
- State Government, Port Jefferson Station
- Stationery & Office Supplies, Port Jefferson Station
- Steak House Restaurants, Port Jefferson Station
- Stereo, Audio & Video Equipment Dealers & Stores, Port Jefferson Station
- Stock & Bond Brokers & Dealers, Port Jefferson Station
- Stocks & Bond Brokers, Port Jefferson Station
- Stress Management & Counseling, Port Jefferson Station
- Substance Abuse Clinics, Port Jefferson Station - Alcoholism, Addiction & Drug Abuse Treatment Centers
- Surgical Supplies & Equipment, Port Jefferson Station
- Surgical Supplies, Instruments, Tools & Equipment, Port Jefferson Station
- Surveyor Services, Port Jefferson Station - Surveying Service
- Sushi Restaurants, Port Jefferson Station
- Swimming Pool, Sauna & Spa Contractors, Port Jefferson Station
- Swimming Pools Contractors, Port Jefferson Station - Install Inground - Above Ground Pools
- Swimming Pools Repair, Service, Supplies, Sale & Installation, Port Jefferson Station
- Swimming Pools Supplies, Equipment & Accessories, Port Jefferson Station
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