- Sales & Marketing Consultant, Sayville
- Sandwich Shop Restaurants, Sayville
- Scottish & Irish Goods & Products Stores, Sayville
- Seafood Restaurants, Sayville
- Secretarial & Court Reporting Services, Sayville
- Security & Surveillance System & Equipment, Sayville
- Security Alarm Systems - Home & Business, Sayville
- Security Brokers & Dealers, Sayville
- Security Control Systems & Monitoring, Sayville - Polygraph, Lie Detector, CCTV, Fire Sensor Equipment, Etc
- Security Investigative Services, Sayville
- Security Services, Sayville
- Semi-Precious Stones, Sayville
- Senior Citizens Service & Health Organizations, Sayville
- Septic & Cesspool Building & Service, Sayville
- Sewer & Drain Cleaning & Repair, Sayville - Drain Cleaner & Installation Services
- Sewing & Yarn Stores & Supplies, Sayville
- Sheet Metal Contractors, Sayville - Sheet Metal Fabrication
- Sheet Metal Fabricators & Ductwork Contractors, Sayville
- Shoe Dyers, Sayville
- Shoe Repair Shops, Sayville
- Shoe Stores, Sayville - Mens, Womens & Kids Shoes
- Shopping & Shopping Services, Sayville
- Siding Contractors, Sayville - Vinyl Siding, Wood, Metal & Aluminum Siding Contractors - Installation & Repair
- Signs, Sayville
- Snacks & Desserts, Sayville
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- Social Clubs & Organizations, Sayville
- Social Services & Welfare, Sayville
- Social Workers & Services, Sayville
- Societies & Foundation Associations, Sayville
- Special Events & Party Supply Rental, Sayville
- Special Interest Schools Or Instruction, Sayville
- Specialty Stores, Sayville
- Speech & Hearing Specialists, Sayville
- Speech Pathologists, Sayville - Speech & Language Therapy
- Sporting & Recreational Camps, Sayville
- Sporting Goods Equipment Rental, Sayville
- Sporting Goods Stores, Sayville
- Sports Medicine, Sayville - Doctors, Physicians & Surgeons
- Sportswear Clothing Stores, Sayville - Sports Clothes
- Sprinkler System Contractors, Sayville - Garden & Lawn Sprinkler System Installation & Repair
- Steel Erection Contractors, Sayville - Steel Erectors
- Stereo, Audio & Video Equipment Dealers & Stores, Sayville
- Stock & Bond Brokers & Dealers, Sayville
- Stocks & Bond Brokers, Sayville
- Surfboard & Windsurfing Equipment Shops, Sayville
- Surveyor Services, Sayville - Surveying Service
- Swimming Pool, Sauna & Spa Contractors, Sayville
- Swimming Pools Contractors, Sayville - Install Inground - Above Ground Pools
- Swimming Pools Repair, Service, Supplies, Sale & Installation, Sayville
- Swimming Pools Supplies, Equipment & Accessories, Sayville
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