- Machine Shop & Tool Repair Service, Tupper Lake
- Machinery, Supplies & Equipment - Business Production Related, Tupper Lake
- Manufacturing, Tupper Lake
- Marine Supplies & Equipment, Tupper Lake - Boat Supplies
- Marriage & Family Counselors, Tupper Lake
- Martial Arts & Self Defense Schools, Tupper Lake
- Masonry Materials & Supplies, Tupper Lake
- Massage Therapists & Professional, Tupper Lake
- Massage Therapy, Tupper Lake
- Medical Alert Systems, Tupper Lake - Medical Alarms - PERS
- Medical Groups & Clinics, Tupper Lake - Medical & Health Centers
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- Medical Supplies & Equipment, Tupper Lake
- Membership Sports & Recreation Clubs, Tupper Lake
- Mental Retardation & Developmentally Disabled Services, Tupper Lake
- Miscellaneous Government, Tupper Lake
- Miscellaneous Professional, Tupper Lake
- Motor Vehicle, Tupper Lake
- Motor Vehicle Rental & Leasing, Tupper Lake
- Movie Theaters, Tupper Lake
- Moving Truck Rental , Tupper Lake
- Muffler Shop & Exhaust Systems, Tupper Lake
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