- Obstetricians & Gynecologists, East Meadow - Ob-Gyn Doctors, Physicians & Surgeons (Obstetrics & Gynecology)
- Office Supplies, Equipment & Office Furniture Stores, East Meadow
- Oil Change & Lubrication, East Meadow - Auto Oil & Quick Lube
- Ophthalmic Goods, East Meadow
- Ophthalmologists, East Meadow - Eye Doctors, Physicians & Surgeons (Ophthalmology)
- Optical Stores - Eyeglasses, Lenses & Sunglasses, East Meadow
- Opticians, East Meadow
- Optometrists, East Meadow - Eye Doctors, Physicians & Surgeons (Optometry)
- Optometry Clinics, East Meadow - Eye Clinics
- Organizing Services & Products – Household & Business, East Meadow
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- Ornamental Nursery, East Meadow
- Ornamental Nursery Services, East Meadow
- Orthodontist, East Meadow - Teeth Straightening, Invisalign & Dental Braces
- Orthopedists, East Meadow - Orthopedic Surgery Doctors, Physicians & Surgeons
- Orthotics and Prosthetics, East Meadow
- Other Building Materials & Supplies, East Meadow
- Outdoor & Lawn & Garden Equipment Repair & Service, East Meadow
- Outdoor Equipment & Accessories, East Meadow
- Outpatient Services, East Meadow - Outpatient Care
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