- Sand Gravel & Aggregate, Frewsburg
- Screen Houses, Frewsburg
- Screen Printing, Frewsburg
- Security & Surveillance System & Equipment, Frewsburg
- Security Alarm Systems - Home & Business, Frewsburg
- Security Control Systems & Monitoring, Frewsburg - Polygraph, Lie Detector, CCTV, Fire Sensor Equipment, Etc
- Security Services, Frewsburg
- Septic Tanks & Systems, Frewsburg - Wholesale, Dealers & Suppliers
- Sewing & Yarn Stores & Supplies, Frewsburg
- Sheet Metal, Frewsburg
- Sheet Metal Contractors, Frewsburg - Sheet Metal Fabrication
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- Sheet Metal Fabricators & Ductwork Contractors, Frewsburg
- Shopping & Shopping Services, Frewsburg
- Siding Contractors, Frewsburg - Vinyl Siding, Wood, Metal & Aluminum Siding Contractors - Installation & Repair
- Smelters & Refiners Precious Metals, Frewsburg
- Snacks & Desserts, Frewsburg
- Social Services & Welfare, Frewsburg
- Societies & Foundation Associations, Frewsburg
- Specialty Animal Services, Frewsburg
- Specialty Stores, Frewsburg
- Sporting Goods Stores, Frewsburg
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