- Dairy Products - Wholesale & Retail, Jamestown
- Dance Companies, Jamestown
- Data Networking, Jamestown
- Data Processing Security Storage, Jamestown
- Data Processing Services, Jamestown
- Day Spas, Jamestown
- Debt Consolidation, Jamestown
- Decorating & Designing Services, Jamestown
- Decorative Wood Products Manufacturers, Jamestown
- Delicatessen Restaurants, Jamestown
- Dentists, Jamestown
- Department Stores, Jamestown
- Developmental Children Services, Jamestown
- Developmental Disabilities, Jamestown
- Developmentally Disabled Information & Services, Jamestown
- Digital Printing & Imaging Service, Jamestown
- Diner Restaurants, Jamestown
- Direct Mail Advertising Services, Jamestown
- Disabled Persons Assistive Services, Jamestown
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- Disc Jockeys, Jamestown
- Discount Stores, Jamestown - Clothing, Grocery, Furniture, Etc
- Dispensing Machines, Jamestown
- Diving Instruction, Jamestown
- Divorce & Family Law Attorneys & Lawyers, Jamestown
- Doctorate Degree, Jamestown
- Doctors, Physicians & Surgeons, Jamestown
- Dogs, Jamestown
- Donuts, Jamestown
- Door & Gate Operating Devices, Jamestown
- Door Installation & Repair, Jamestown - Garage, Glass, Screen, Sliding, French, Closet, Front, Storm, Interior & Exterior Doors
- Doors & Door Frames, Jamestown - Exterior, Interior, French, Front Entry, Patio, Storm, Garage & Sliding Glass Doors
- Drafting Services, Jamestown
- Drinking Establishments, Jamestown
- Drive Shafts, Jamestown
- Drugs, Pharmaceutical Products & Toiletries - Wholesale & Manufacturers, Jamestown
- Dry Cleaning & Laundry, Jamestown - Dry Cleaners
- Durable & Non Durable Goods & Products, Jamestown
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