- Savings & Loan Associations, Southold
- Savings Banks, Southold
- Seafood Restaurants, Southold
- Security & Surveillance System & Equipment, Southold
- Security Alarm Systems - Home & Business, Southold
- Security Brokers & Dealers, Southold
- Security Control Systems & Monitoring, Southold - Polygraph, Lie Detector, CCTV, Fire Sensor Equipment, Etc
- Security Services, Southold
- Senior Citizens Service & Health Organizations, Southold
- Septic & Cesspool Building & Service, Southold
- Sewer & Drain Cleaning & Repair, Southold - Drain Cleaner & Installation Services
- Shopping & Shopping Services, Southold
- Signs, Southold
- Smoke Odor Counteracting Services, Southold
- Smoked Meat Restaurants, Southold
- Social Services & Welfare, Southold
- Societies & Foundation Associations, Southold
- Special Events & Party Supply Rental, Southold
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- Special Interest Schools Or Instruction, Southold
- Specialty Animal Services, Southold
- Specialty Communication Companies & Services, Southold
- Specialty Stores, Southold
- Speech & Hearing Specialists, Southold
- Sporting Goods Equipment Rental, Southold
- Sporting Goods Stores, Southold
- Sprinkler System Contractors, Southold - Garden & Lawn Sprinkler System Installation & Repair
- Staffing & Support Services, Southold
- State Government, Southold
- Steak House Restaurants, Southold
- Stock & Bond Brokers & Dealers, Southold
- Stocks & Bond Brokers, Southold
- Stove, Oven, Range & Cooktop Parts & Supplies, Southold
- Surgical Supplies & Equipment, Southold
- Surgical Supplies, Instruments, Tools & Equipment, Southold
- Surveyor Services, Southold - Surveying Service
- Swimming Pools Supplies, Equipment & Accessories, Southold
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