- Dance Companies, Tonawanda
- Darts & Dart Boards Supplies, Tonawanda
- Data Communications Service, Equipment, Supplies & Sales, Tonawanda
- Data Processing Services, Tonawanda
- Day Spas, Tonawanda
- Debt Adjusters, Tonawanda
- Debt Consolidation, Tonawanda
- Debt Management Assistance & Services, Tonawanda
- Delicatessen Restaurants, Tonawanda
- Dental Supplies & Equipment, Tonawanda
- Dentists, Tonawanda
- Deodorant, Disinfectants & Germicides, Tonawanda
- Department Stores, Tonawanda
- Designers, Tonawanda
- Developmental Disabilities, Tonawanda
- Developmentally Disabled Information & Services, Tonawanda
- Dialysis Clinics, Tonawanda - Kidney Dialysis Centers
- Diamonds & Precious & Semi-Precious Stones, Tonawanda
- Die Cutting Machine, Supplies & Equipment, Tonawanda
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- Dies, Tonawanda
- Direct Mail Advertising Services, Tonawanda
- Disabled Persons Assistive Services, Tonawanda
- Disc Jockeys, Tonawanda
- Discount Stores, Tonawanda - Clothing, Grocery, Furniture, Etc
- Displays & Display Installation Service, Tonawanda - Trade Show Displays
- Doctors, Physicians & Surgeons, Tonawanda
- Donuts, Tonawanda
- Door & Gate Operating Devices, Tonawanda
- Doors & Door Frames, Tonawanda - Exterior, Interior, French, Front Entry, Patio, Storm, Garage & Sliding Glass Doors
- Drapery Blinds & Shades Installation & Repair, Tonawanda
- Drinking Establishments, Tonawanda
- Drugs, Pharmaceutical Products & Toiletries - Wholesale & Manufacturers, Tonawanda
- Dry Cleaning & Laundry, Tonawanda - Dry Cleaners
- Drywall Equipment & Supplies, Tonawanda
- Drywall, Insulation & Plaster Contractors, Tonawanda - Installation & Repair Services
- Durable & Non Durable Goods & Products, Tonawanda
- Durable Goods & Products, Tonawanda
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